MLS® Mphi 75Multiwave Locked System
The MLS® Mphi 75 by ASA Laser is a Class IV medical laser device that simultaneously emits two synchronised therapeutic wavelengths — 808 nm and 905 nm — to deliver clinically proven pain relief, anti-inflammatory action, and accelerated tissue repair from the very first session.
MLS® Mphi 75
ASA Laser · Class IV Medical Device
Two Synchronised Wavelengths. One Locked Beam.
The 'Locked' in MLS® refers to the patented synchronisation of both wavelengths into a single emission — producing a combined therapeutic effect that is greater than the sum of its parts.
Continuous Emission (CW)
Anti-Inflammatory & Anti-Oedema
The 808 nm wavelength is emitted in continuous wave mode. It penetrates deeply into soft tissues (tendons, ligaments, muscles, joint capsule) and acts primarily on inflammatory mediators. It suppresses the production of prostaglandin E2 (PGE2), interleukin-1β (IL-1β), and tumour necrosis factor-alpha (TNF-α) — the key biochemical drivers of tissue inflammation. The continuous emission also triggers vasodilation and enhanced microcirculation, accelerating the removal of inflammatory metabolites from injured tissue.
Pulsed Emission (PW)
Analgesic — Rapid Pain Relief
The 905 nm wavelength is emitted in pulsed mode, allowing deeper tissue penetration with lower thermal risk. It exerts its primary analgesic effect through two mechanisms: first, it stimulates the release of endogenous opioids (β-endorphin, enkephalins) at the spinal cord level, raising the pain threshold; second, it acts on free nerve endings, reducing the speed of pain signal transmission along C and Aδ fibres. Patients frequently report significant pain reduction from the very first session.
808 nm resolves inflammation · 905 nm eliminates pain · Emitted simultaneously = synergistic healing at every pulse
How Photobiomodulation Works
MLS® laser therapy works through photobiomodulation (PBM) — the use of specific wavelengths of light to trigger measurable biological responses in cells and tissues.
Mitochondrial Activation & ATP Production
Laser photons are absorbed by cytochrome c oxidase (CCO) in the mitochondrial electron transport chain. This interaction dissociates nitric oxide from CCO, restoring oxygen metabolism and dramatically increasing ATP (adenosine triphosphate) production — the primary fuel for all cellular repair processes. Injured cells, which are in a state of metabolic stress, respond most strongly to this stimulus.
Tissue Repair & Collagen Synthesis
The energy boost from ATP upregulates fibroblast proliferation and protein synthesis. Fibroblasts produce collagen — the structural scaffold for all connective tissue (tendons, ligaments, cartilage, skin). MLS® therapy accelerates the organised deposition of collagen fibres along stress lines, producing mechanically superior scar tissue and faster functional recovery compared to natural healing alone.
Inflammation Resolution
MLS® actively resolves inflammation rather than simply masking it. By modulating NF-κB signalling pathways and reducing prostaglandin synthesis, the laser converts chronic, unresolved inflammation into the regenerative phase of healing. This is particularly significant for chronic tendinopathies and osteoarthritis where persistent low-grade inflammation blocks tissue recovery.
Neovascularisation & Circulation
MLS® stimulates nitric oxide (NO) production in blood vessel walls, causing local vasodilation and increased microvascular blood flow. It also upregulates vascular endothelial growth factor (VEGF), promoting the formation of new capillaries (angiogenesis) in areas of healing tissue. This enhanced perfusion delivers oxygen, growth factors, and immune cells to the repair site, while clearing metabolic waste products.
Conditions Treated
MLS® laser therapy has a broad range of evidence-based clinical applications across musculoskeletal, neurological, and post-surgical conditions.
Tendon & Ligament
- Achilles tendinopathy
- Patellar tendinopathy
- Rotator cuff tendinopathy
- Plantar fasciitis
- Tennis & golfer's elbow
- Ligament sprains (grade I–II)
Muscle & Soft Tissue
- Muscle strains & tears
- Trigger point therapy
- Myofascial pain syndrome
- Delayed onset muscle soreness (DOMS)
- Contusions & haematomas
- Scar tissue & adhesions
Joint & Bone
- Osteoarthritis (knee, hip, shoulder)
- Rheumatoid arthritis flares
- Post-fracture bone healing support
- Post-surgical joint recovery
- Sacroiliac joint dysfunction
- Temporomandibular joint (TMJ) pain
Spine & Nerve
- Cervical & lumbar disc herniation
- Sciatic nerve pain
- Carpal tunnel syndrome
- Peripheral neuropathy
- Post-surgical nerve recovery
- Chronic neck & back pain
Clinical Benefits
Significant pain relief typically from the 1st session
Tissue healing 2–3× faster than natural recovery
Completely painless — no heat sensation, no needles, no surgery
No known side effects — safe for all ages including elderly patients
Treats the root cause — not just symptoms — through cellular repair
Effective for chronic conditions that haven't responded to other treatments
CE-marked Class IV medical device — EU MDR approved
Cumulative benefit — each session builds on the previous biological response
Ideal for these patients
MLS® laser therapy is particularly valuable for patients who have tried conventional treatment without satisfactory results, those seeking a non-pharmacological pain solution, and athletes who need the fastest possible recovery without compromising tissue quality.
What to Expect
Session Duration
10–25 minutes depending on area and condition
Frequency
2–3 times per week for acute; 1–2x for chronic
Course Length
5–8 sessions (acute) · 8–12+ sessions (chronic)
Location
In-clinic only · Protective eyewear provided
Combined With
Manual therapy, electrotherapy, exercise in same session